Many of our participants are first time volunteers. As a result, we have been able to develop a database of answers for some of the great questions we are asked regularly. Here you will find common questions and answers volunteers often ask.

Choosing to participate in a clinical trial is an important personal decision. The following frequently asked questions provide introductory information about clinical trials. In addition, it is often helpful to talk to a physician, family members, or friends about deciding to join a trial. After identifying some trial options, the next step is to contact the study research staff and ask questions about specific trials.

• What is a clinical trial?
• Why participate in a clinical trial?
• Where do the ideas for trials come from?
• Who sponsors clinical trials?
• What is a protocol?
• What is a placebo?
• What is a control or control group?
• What are the different types of clinical trials?
• What are the phases of clinical trials?
• What is an "expanded access" protocol?

For those considering participation in a clinical trial, the following frequently asked questions are important in understanding the role of the participant and the unique process of clinical trials.

• Who can participate in a clinical trial?
• What happens during a clinical trial?
• What is informed consent?
• What kind of preparation should a potential participant make for the meeting with the research coordinator or doctor?
• What should people consider before participating in a trial?
• Does a participant continue to work with a primary health care provider while in a trial?
• What are side effects and adverse reactions?
• What are the benefits and risks of participating in a clinical trial?
• How is the safety of the participant protected?
• Can a participant leave a clinical trial after it has begun?

For more information visit the National Institute of Health's Clinical Trial Website.